Epigenetics and Life-Long Events

Epigenetic modifications to genes can be transient, altering gene expression for a short period of time. But some changes are very stable and may last for the entire lifetime of an individual. In this session we will examine some of the evidence that addresses how epigenetics can create and maintain long-term patterns of gene expression, and the potential effects this has. Topics will include the adult consequences of early abuse or neglect, the changes in gene expression that are induced by drugs of addiction and the delayed clinical responses to antidepressants. The potentially reversible nature of epigenetic modifications to genes means that there is the scope for altering these responses, but will this increased mechanistic understanding change practice?

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Dr Nessa Carey

Nessa Carey has a science PhD from the University of Edinburgh and is a Visiting Professor at Imperial College London. Between 2001 and 2014 she worked in the UK biotech and pharmaceutical sectors, where much of her time was spent in translating the latest findings in epigenetics into opportunities to create new therapies to improve human health.


This video presentation is from Neurobiology and its Applications to Psychotherapy - II. To find out more about this module click here.